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Should the clinical and laboratory analysis position towards a neoplastic origin, clonality needs to be evaluated through stream cytometry. A number of clonal B-cell Diseases may be determined according to surface protein markers with this kind of Investigation (Table 1). The management of clonal Issues of CLL phenotype is the main target of the rest of the evaluation.
Are BTK and PLCG2 mutations vital and adequate for ibrutinib resistance in Serious lymphocytic leukemia?